DEEPMIND ALPHAFOLD: The Next Giant Leap By Humans

Reading Time: 3 minutes

It has nearly taken hundreds of centuries to get where we are today. From the invention of the wheel to the fastest train with speed of 603 Kmph, from the discovery of fire to landing on the moon, all the technological advances that you use in everyday life, unnoticed, is the result of enthusiastic effort and genius of the great legacy. Artificial intelligence is certainly is the next giant step in that series, the rate of technological advancement would be ever high! Following the one such initiative:

  • DeepMind is the world leader in artificial intelligence research and its application for positive impact on the world.
  • DeepMind was founded in London and backed by some of the most successful technology entrepreneurs in the world and have been acquired by Google in 2014.
  • DeepMind, an AI lab is the complete outsider to the field of molecular biology, beat top pharmaceutical companies like Novartis, Pfizer, etc. at predicting protein structures.
  • DeepMind has brought together experts from fields if structural biology, physics, machine learning to apply cutting edge techniques to predict the 3D structure of a protein based on its genetic sequence.
  • DeepMind Alpha Fold is the system which uses vast genomic data to predict protein structure.
  • CASP (Critical assessment of structure prediction) is a virtual protein folding Olympics, where the aim is to predict the 3D structure of the protein based on its genetic sequence data.
  • DeepMind has won the CASP13 protein folding competition.
  • Alpha Fold scores 127.99 was 20 points higher than the second-ranked team, achieving what CASP called “unprecedented progress in the ability of computational methods to predict protein structure”.

     What is protein folding problem?

Proteins are our bodies building blocks and perform a vast array of essential functions.

A protein molecule is made of a string of smaller components called amino acids, which fold into the molecule’s 3D shape. The protein folding problem involves determining how the string of amino acids encodes the 3D shape of a protein molecule. This can produce a better understanding of proteins and enable scientists to change their function for the good of our bodies. For example in treating diseases caused by misfolded proteins, such as Alzheimer’s, Parkinson’s, Huntington’s and cystic fibrosis.

The protein folding problem is regarded as one of the grandest biochemistry challenges of the last 50 years. Current approaches include using algorithms to compute the 3D structure of proteins with amino acids sequence data, or using X-ray crystallography and other techniques to image a protein structure.

DEEPMIND ALPHAFOLD: The Next Giant Leap By Humans

    The DeepMind’s approach:

  • DeepMind researchers used deep neural network to learn the correlation between the shape of a protein molecule and its amino acid sequence.
  • The physical properties of a protein molecule include the distance between pairs of amino acids and the angles between chemical bonds that connect those amino acids.

DEEPMIND ALPHAFOLD: The Next Giant Leap By Humans

  • The model came up with a score that estimates the accuracy of a proposed protein structure, then used gradient descent a common deep learning algorithm that finds the minimum of a function to optimize that score.
  • DeepMind has been working on protein folding for two years and has significantly advanced the development of protein engineering.

Thanks for reading.



Artificial Intelligence boon or curse?????

Reading Time: 3 minutes

This debate on whether artificial intelligence is good or bad would be among most brainstorming debate in CEV history. At one time we were with the idea that artificial intelligence is an ultimate tool for human to make an earth full of good things and in next moment we felt that it is the last human invention. Debate was held on Friday evening, 31 August.

Points followed for increased exploration in this field were-

Artificial Intelligence boon or curse?????




  1. Artificial intelligence is tool for humanity that can prove to be his most ingenious technological advancement and have potential to help us in sustaining our civilisation much longer.
  2. With the aid of their superhuman capability of enormous computation we can employ them to find solutions to compelling questions like how to cure  AIDS/HIV, how to reduce global warming, alternative for fossil fuels, substitute for plastics,how to reduce ozone layer depletion, etc.
  3. We can exploit this technology in those field where there is great risk of human life like space exploration missions, utility and power linemen, firefighters, miners, search and rescue and so on.
  4.  Now since they are non living things we can use them in crummy works which in many cases lead to social indifferences in our society like slaughterhouse workers, sanitation workers, personal transport drivers, embalmer, garbage collector, sewage cleaner, etc.
  5. Artificial intelligence can play its greatest role in pharmaceutical industry like new methods to treat cancer which are less painful, epidemic control, new medicines with fast cure capability and very less side effects which otherwise will require tedious human labor and time.
  6. Technological change may eliminate specific jobs, but it has always created more in the process, we had witnessed it in past.

Points that indicated that artificial intelligence is the greatest threat to human being ever-

Artificial Intelligence boon or curse?????

  1. These machines are now so advanced that they too have feelings, and in case they feel offended by humans they might declare war against us.
  2. These machines are not subject to ageing so a particular machine can increase its capabilities to tremendous extent.
  3. Another big problem is that it will erase all the job opportunity for the middle class people like car drivers, etc.
  4. Facebook artificial robots were made to shut down forcefully as they were found talking to each other in strange language that was not understood by humans. So, this give us glimpses of what they could be capable of in future. A chunk of  communication they had with them-Bob: i can i i everything else . . . . . . . . . . . . . .Alice: balls have zero to me to me to me to me to me to me to me to me to

    Bob: you i everything else . . . . . . . . . . . . .

Conclusion: Currently in the world Artificial intelligence is still debated topic, there is no doubt that they have a great potential to serve human civilization and make life very convenient, like speech recognition, face recognition all these are features of it. Numerous tech-giants like Google, Amazon, Netflix, Facebook,  Pandora, Tesla are currently utilizing it for more user friendly services. But on the same time there have being events and prediction that uncontrolled and injudicious use will some day create danger for us, hence it should be taken care that artificial intelligence should be employed only in those field where their use are indispensable and that too under vigilant supervision.

Artificial Intelligence boon or curse?????

Minutes by-

Rahul, electrical engg.(2nd year), SVNIT.

(Images are copied randomly, objections are accepted!)

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